MEDICINE
An anticancer drug: a world first water-soluble prodrug type curcumin injectable which can achieve the incomparable bioavailability as a free form of curcumin.
One of the major compounds of the well-known curry spice turmeric is curcumin. The curcumin is known for its anti-cancer properties, and so, developments/experiments are widely conducted for taking advantage of these functionalities for applying anti-cancer drugs. However, up to now it hasn’t been possible to obtain the expected anti-cancer efficiency due to the low bioavailability caused by the high and fast excretions.
In collaboration with Kyoto University, CerabioPharma is a water-soluble prodrug that artificially synthesizes a conjugate that dramatically improves the bioavailability of a curcumin-free form and changes it to the active ingredient curcumin for the first time in the body. We are developing an injection using curcumin CMG (curcumin monoglucuronide).
In vivo, it has achieved an increase in the active ingredient in blood about 1,000 to 10,000 times that of conventional drugs, and is effective as an anticancer drug and in the preventive and therapeutic effects of cytokine storms, which are factors that make infectious diseases more severe. Tests have proven great effectiveness.
FUNCTIONAL MATERIALS - FOOD
Using our technical knowledge and know-how about natural compound, we will increase the bioavailability of the functional materials. We will apply not only our technologies/ideas to supplements, but also daily food such as chocolate, gummi candies, drinks etc.
